Advantages of proteins being disordered
نویسندگان
چکیده
منابع مشابه
The Advantages of Being Vectorlike
Consider an asymptotically free gauge theory with global symmetry group G. At short distances this gauge theory allows a perturbative definition. One fundamental question at long distances relates to how the symmetry group G is realized in the vacuum. Virtually no progress has been made in answering this question from first principles in QCD, the gauge theory responsible for all hadronic and nu...
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متن کاملIntrinsically disordered proteins.
Our understanding of protein function has been predominated by the view that proteins need to adopt a defined three dimensional structure to be able to carry out their function. Indeed, crystal structures of numerous proteins have been instrumental in establishing the structure– function paradigm. For example, the structures of numerous enzymes have highlighted the need for particular chemical ...
متن کاملIntrinsically Disordered Proteins
In the same way that neither a messy lab bench nor a clean one is a reliable indicator of a researcher’s productivity, a protein’s function cannot be judged solely on the basis of its neatly folded and stable domains. As evidenced by recent work discussed in this Select, we are learning that intrinsically disordered regions feature in many of the cell’s most productive multitaskers, proteins wh...
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Avian brood parasites lay their eggs in the nests of other species (hosts) which incubate and rear the brood-parasite offspring. This reproductive strategy directly reduces the cost of reproduction (e.g. parental care) and, therefore, may be subject to natural selection. I discuss three additional advantages arising from the fact that host and parasite are different species and that, therefore,...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2014
ISSN: 0961-8368
DOI: 10.1002/pro.2443